ARG66601
anti-LYVE1 antibody
anti-LYVE1 antibody for Flow cytometry,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
参考文献1
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes LYVE1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-Fr, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LYVE1 |
| 抗原物种 | Human |
| 抗原 | Recombinant Human LYVE1. |
| 偶联标记 | Un-conjugated |
| 別名 | Lymphatic vessel endothelial hyaluronic acid receptor 1; Hyaluronic acid receptor; LYVE-1; XLKD1; HAR; Extracellular link domain-containing protein 1; CRSBP-1; Cell surface retention sequence-binding protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9Y5Y7 Human Lymphatic vessel endothelial hyaluronic acid receptor 1 |
|---|---|
| 基因名称 | LYVE1 |
| 全名 | lymphatic vessel endothelial hyaluronan receptor 1 |
| 背景介绍 | This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface. [UniProt] |
| 预测分子量 | 35 kDa |
| 翻译后修饰 | O-glycosylated. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG66601 anti-LYVE1 antibody IHC-Fr image
Immunohistochemistry: Cryo sections of Human colon carcinoma tissue stained with ARG66601 anti-LYVE1 antibody (red) and anti-Human CD31 (green). A: CD31; B: LYVE1; C: Merged.
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ARG66601 anti-LYVE1 antibody WB image
Western blot: Recombinant Human sLYVE1 and Mouse sLYVE1 stained with ARG66601 anti-LYVE1 antibody. There is more or less no cross reactivity with Mouse LYVE1.
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ARG66601 anti-LYVE1 antibody FACS image
Flow Cytometry: Human dermal microvascular endothelial cells (HDMVEC) stained with ARG66601 anti-LYVE1 antibody.
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ARG66601 anti-LYVE1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human intestine (border area of a colon carcinoma) stained with ARG66601 anti-LYVE1 antibody.
文献引用
BRAF V600E mutant colorectal cancer cells mediate local immunosuppressive microenvironment through exosomal long noncoding RNAs
IHC-P / Human
