概述

产品描述	Rabbit Polyclonal antibody recognizes LYVE1
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	LYVE1
抗原物种	Human
抗原	Synthetic peptide derived from Human LYVE1.
偶联标记	Un-conjugated
別名	Lymphatic vessel endothelial hyaluronic acid receptor 1; Hyaluronic acid receptor; LYVE-1; XLKD1; HAR; Extracellular link domain-containing protein 1; CRSBP-1; Cell surface retention sequence-binding protein 1

应用说明

应用建议	应用 推荐稀释比 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	A549

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 10894 Human LYVE1 GeneID: 114332 Mouse LYVE1 Swiss-port # Q8BHC0 Mouse Lymphatic vessel endothelial hyaluronic acid receptor 1 Swiss-port # Q9Y5Y7 Human Lymphatic vessel endothelial hyaluronic acid receptor 1
基因名称	LYVE1
全名	lymphatic vessel endothelial hyaluronan receptor 1
背景介绍	This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008]
生物功能	Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. [UniProt]
细胞定位	Membrane; Single-pass type I membrane protein. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface. [UniProt]
预测分子量	35 kDa
翻译后修饰	O-glycosylated. [UniProt]

检测图片 (1) Click the Picture to Zoom In