ARG44539
anti-LTB antibody
anti-LTB antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes LTB |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LTB |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide from Human |
| 偶联标记 | Un-conjugated |
| 別名 | LTB; Lymphotoxin Beta; TNFSF3; TNFC; P33; Tumor Necrosis Factor Ligand Superfamily Member 3; TNF Superfamily Member 3; Necrosis Factor C; Lymphotoxin-Beta; LT-Beta; TNF-C |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 40% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LTB |
| 全名 | Lymphotoxin Beta |
| 背景介绍 | Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| 生物功能 | Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional. |
| 细胞定位 | Membrane |
| 预测分子量 | 25 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG44539 anti-LTB antibody IHC-P image
Immunohistochemistry: Human liver stained with ARG44539 anti-LTB antibody.
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ARG44539 anti-LTB antibody IHC-P image
Immunohistochemistry: Human tonsils stained with ARG44539 anti-LTB antibody.
