ARG41203
anti-LPIN2 / Lipin 2 antibody
anti-LPIN2 / Lipin 2 antibody for Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes LPIN2 / Lipin 2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LPIN2 / Lipin 2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 180-400 of Human LPIN2 / Lipin 2 (NP_055461.1). |
| 偶联标记 | Un-conjugated |
| 別名 | EC 3.1.3.4; Phosphatidate phosphatase LPIN2; Lipin-2 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | A549 | ||||
| 实际分子量 | 110 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LPIN2 |
| 全名 | lipin 2 |
| 背景介绍 | Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism (By similarity). [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum membrane. Note=Translocates to endoplasmic reticulum membrane with increasing levels of oleate. [UniProt] |
| 预测分子量 | 99 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG41203 anti-LPIN2 / Lipin 2 antibody WB image
Western blot: 25 µg of A549 cell lysate stained with ARG41203 anti-LPIN2 / Lipin 2 antibody at 1:1000 dilution.
