ARG54850

anti-LPAR2 / EDG4 antibody

anti-LPAR2 / EDG4 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Gene Regulation antibody; Signaling Transduction antibody

概述

产品描述 Rabbit Polyclonal antibody recognizes LPAR2 / EDG4
反应物种 Hu
预测物种 Mk
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 LPAR2 / EDG4
抗原物种 Human
抗原 KLH-conjugated synthetic peptide corresponding to aa. 3-32 (N-terminus) of Human EDG4.
偶联标记 Un-conjugated
別名 LPA2; EDG4; Lysophosphatidic acid receptor Edg-4; EDG-4; Lysophosphatidic acid receptor 2; LPA receptor 2; LPA-2

应用说明

应用建议
应用 推荐稀释比
IHC-PAssay-dependent
WB1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 MDA-MB-231

属性

形式 Liquid
纯化 Purification with Protein G.
缓冲液 PBS and 0.09% (W/V) Sodium azide
抗菌剂 0.09% (W/V) Sodium azide
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 9170 Human LPAR2

Swiss-port # Q9HBW0 Human Lysophosphatidic acid receptor 2

基因名称 LPAR2
全名 lysophosphatidic acid receptor 2
背景介绍 This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
生物功能 Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. [UniProt]
细胞定位 Cell surface. Cell membrane; Multi-pass membrane protein. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA colocalizes with RALA in the endocytic vesicles
研究领域 Gene Regulation antibody; Signaling Transduction antibody
预测分子量 39 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG54850 anti-LPAR2 / EDG4 antibody (N-term) IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human breast cancer tissue stained with ARG54850 anti-LPAR2 / EDG4 antibody (N-term).

  • ARG54850 anti-LPAR2 / EDG4 antibody (N-term) WB image

    Western blot: 35 µg of MDA-MB-231 cell lysate stained with ARG54850 anti-LPAR2 / EDG4 antibody (N-term) at 1:1000 dilution.