ARG46259
anti-LNPEP antibody
anti-LNPEP antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes LNPEP |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LNPEP |
| 抗原物种 | Human |
| 抗原 | A 15 amino acid synthetic peptide within aa. 900 - 950 of human LNPEP. |
| 偶联标记 | Un-conjugated |
| 別名 | leucyl/cystinyl aminopeptidase; LNPEP; CAP; IRAP; PLAP; P-LAP; OTASE; Leucyl-cystinyl aminopeptidase; Insulin-regulated membrane aminopeptidase; Cystinyl aminopeptidase |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -309°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LNPEP |
| 全名 | leucyl/cystinyl aminopeptidase |
| 背景介绍 | This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| 生物功能 | Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain. [UniProt] |
| 细胞定位 | Cell membrane. [UniProt] |
| 预测分子量 | 117 kDa |
| 翻译后修饰 | Phosphoprotein; Glycoprotein; Acetylation. [UniProt] |
