ARG44402
anti-LIN7C antibody
anti-LIN7C antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes LIN7C |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LIN7C |
| 抗原物种 | Human |
| 抗原 | Human LIN7C recombinant protein (aa. sequence: M1-A73). |
| 偶联标记 | Un-conjugated |
| 別名 | LIN7C; Lin-7 Homolog C, Crumbs Cell Polarity Complex Component; MALS-3; VELI3; LIN-7-C; LIN-7C; Mammalian Lin-Seven Protein 3; Vertebrate Lin-7 Homolog 3; Protein Lin-7 Homolog C; LIN-7 Protein 3 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LIN7C |
| 全名 | Lin-7 Homolog C, Crumbs Cell Polarity Complex Component |
| 背景介绍 | Enables L27 domain binding activity and cytoskeletal protein binding activity. Involved in morphogenesis of an epithelial sheet. Located in cell-cell junction; cytoplasm; and plasma membrane. Part of MPP7-DLG1-LIN7 complex. |
| 生物功能 | Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules. |
| 细胞定位 | Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse, Tight junction |
| 预测分子量 | 22 kDa |
| 翻译后修饰 | Acetylation |
检测图片 (5) Click the Picture to Zoom In
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ARG44402 anti-LIN7C antibody IHC-P image
Immunohistochemistry: Human bladder urothelial carcinoma stained with ARG44402 anti-LIN7C antibody at 2 μg/mL dilution.
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ARG44402 anti-LIN7C antibody FACS image
Flow Cytometry: HP-1 stained with ARG44402 anti-LIN7C antibody at 1 μg/10^6 cells dilution.
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ARG44402 anti-LIN7C antibody WB image
Western blot: RT4 stained with ARG44402 anti-LIN7C antibody at 0.5 μg/mL dilution.
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ARG44402 anti-LIN7C antibody IHC-P image
Immunohistochemistry: Rat kidney stained with ARG44402 anti-LIN7C antibody at 2 μg/mL dilution.
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ARG44402 anti-LIN7C antibody WB image
Western blot: Rat brain stained with ARG44402 anti-LIN7C antibody at 0.5 μg/mL dilution.
