ARG55337
anti-LIG1 / DNA ligase 1 antibody
anti-LIG1 / DNA ligase 1 antibody for ICC/IF,Western blot and Human,Mouse
Gene Regulation antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes LIG1 / DNA ligase 1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LIG1 / DNA ligase 1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human LIG1 |
| 偶联标记 | Un-conjugated |
| 別名 | EC 6.5.1.1; DNA ligase 1; Polydeoxyribonucleotide synthase [ATP] 1; DNA ligase I |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | 22RV-1 | ||||||
| 实际分子量 | ~ 130 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LIG1 |
| 全名 | ligase I, DNA, ATP-dependent |
| 背景介绍 | This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| 生物功能 | DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. [UniProt] |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 102 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG55337 anti-LIG1 / DNA ligase 1 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG55337 anti-LIG1 / DNA ligase 1 antibody.
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ARG55337 anti-LIG1 / DNA ligase 1 antibody WB image
Western blot: 22RV-1 cell lysate stained with ARG55337 anti-LIG1 / DNA ligase 1 antibody.
