ARG44412

anti-LAP3 antibody

anti-LAP3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes LAP3
反应物种 Hu, Ms, Rat
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 LAP3
抗原物种 Human
抗原 Human LAP3 recombinant protein (aa. sequence: R130-K497).
偶联标记 Un-conjugated
別名 LAP3; Leucine Aminopeptidase 3; LAPEP; Peptidase S; PEPS; LAP; Cysteinylglycine-S-Conjugate Dipeptidase; Cytosol Aminopeptidase; Proline Aminopeptidase; Leucyl Aminopeptidase; Prolyl Aminopeptidase

应用说明

应用建议
应用 推荐稀释比
ICC/IF5 µg/ml
IHC-P2-5 µg/ml
WB0.25-0.5 µg/ml
应用说明 The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purified with Immunogen.
缓冲液 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂 0.05% Sodium azide
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 289668 Rat LAP3

GeneID: 51056 Human LAP3

GeneID: 66988 Mouse LAP3

基因名称 LAP3
全名 Leucine Aminopeptidase 3
背景介绍 Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Located in cytosol; midbody; and nucleoplasm.
生物功能 Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn2+ ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn2+, it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.
细胞定位 Cytoplasm
预测分子量 56 kDa
翻译后修饰 Acetylation, Phosphoprotein

检测图片 (4) Click the Picture to Zoom In

  • ARG44412 anti-LAP3 antibody IHC-P image

    Immunohistochemistry: Human ovarian serous adenocarcinoma stained with ARG44412 anti-LAP3 antibody at 2 μg/mL dilution.

  • ARG44412 anti-LAP3 antibody ICC/IF image

    Immunofluorescence: U2OS stained with ARG44412 anti-LAP3 antibody at 5 μg/mL dilution.

  • ARG44412 anti-LAP3 antibody WB image

    Western blot: Rat live stained with ARG44412 anti-LAP3 antibody at 0.5 μg/mL dilution.

  • ARG44412 anti-LAP3 antibody WB image

    Western blot: Mouse live stained with ARG44412 anti-LAP3 antibody at 0.5 μg/mL dilution.