ARG44219
anti-L3MBTL3 antibody
anti-L3MBTL3 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes L3MBTL3 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | L3MBTL3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human L3MBTL3 |
| 偶联标记 | Un-conjugated |
| Protein Full name | Lethal(3)malignant brain tumor-like protein 3 |
| 別名 | L3MBTL3; L3MBTL Histone Methyl-Lysine Binding Protein 3; KIAA1798; L3MBTL3, Histone Methyl-Lysine Binding Protein; Lethal(3)Malignant Brain Tumor-Like Protein 3; H-L(3)Mbt-Like Protein 3; L3mbt-Like 3; MBT-1; MBT1; L(3)Mbt-Like 3 (Drosophila); L(3)Mbt-Like Protein 3; L(3)Mbt-Like 3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q96JM7 Human Lethal(3)malignant brain tumor-like protein 3 |
|---|---|
| 基因名称 | L3MBTL3 |
| 全名 | L3Mbtl Histone Methyl-Lysine Binding Protein 3 |
| 背景介绍 | This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma. |
| 生物功能 | Is a negative regulator of Notch target genes expression, required for RBPJ-mediated transcriptional repression. |
| 细胞定位 | Nucleus |
| 预测分子量 | 88 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation |
检测图片 (3) Click the Picture to Zoom In
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ARG44219 anti-L3MBTL3 antibody IHC-P image
Immunohistochemistry: Human bladder urothelial carcinoma stained with ARG44219 anti-L3MBTL3 antibody at 2 μg/mL dilution.
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ARG44219 anti-L3MBTL3 antibody WB image
Western blot: Jurkat, HEL, 293T and THP-1 stained with ARG44219 anti-L3MBTL3 antibody at 0.25 μg/mL dilution.
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ARG44219 anti-L3MBTL3 antibody FACS image
Flow Cytometry: U251 stained with ARG44219 anti-L3MBTL3 antibody at 1 μg/1x10^6 cells dilution.
