ARG44396
anti-L3MBTL2 antibody
anti-L3MBTL2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes L3MBTL2 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | L3MBTL2 |
| 抗原物种 | Human |
| 抗原 | Human L3MBTL2 recombinant protein (aa. sequence: E208-Q701). |
| 偶联标记 | Un-conjugated |
| 別名 | L3MBTL2; L3MBTL Histone Methyl-Lysine Binding Protein 2; L3MBTL2, Polycomb Repressive Complex 1 Subunit; Lethal(3)Malignant Brain Tumor-Like Protein 2; H-L(3)Mbt-Like Protein 2; L(3)Mbt-Like Protein 2 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q969R5 Human Lethal(3)malignant brain tumor-like protein 2 |
|---|---|
| 基因名称 | L3MBTL2 |
| 全名 | L3MBTL Histone Methyl-Lysine Binding Protein 2 |
| 背景介绍 | Enables methylated histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including ectoderm development; regulation of histone modification; and stem cell proliferation. Located in nucleus. |
| 生物功能 | Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. |
| 细胞定位 | Nucleus |
| 预测分子量 | 79 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation |
检测图片 (4) Click the Picture to Zoom In
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ARG44396 anti-L3MBTL2 antibody IHC-P image
Immunohistochemistry: Human colorectal adenocarcinoma stained with ARG44396 anti-L3MBTL2 antibody at 2 μg/mL dilution.
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ARG44396 anti-L3MBTL2 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG44396 anti-L3MBTL2 antibody at 5 μg/mL dilution.
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ARG44396 anti-L3MBTL2 antibody WB image
Western blot: 293T andn HeLa stained with ARG44396 anti-L3MBTL2 antibody at 0.5 μg/mL dilution.
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ARG44396 anti-L3MBTL2 antibody IHC-P image
Immunohistochemistry: Human esophageal squamous carcinoma stained with ARG44396 anti-L3MBTL2 antibody at 2 μg/mL dilution.
