ARG67039
anti-L1CAM antibody [SQab30319]
anti-L1CAM antibody [SQab30319] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant rabbit Monoclonal antibody [SQab30319] recognizes L1CAM |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30319 |
| 同位型 | IgG |
| 靶点名称 | L1CAM |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human L1CAM. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Neural cell adhesion molecule L1 |
| 別名 | L1CAM, L1 Cell Adhesion Molecule, NCAM-L1, CAML1, Neural Cell Adhesion Molecule L, CD171 , MIC5, Antigen Identified By Monoclonal Antibody R1, N-CAM-L1, HSAS1, HSAS, MASA, SPG1, S10, CD171 Antigen, N-CAML1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Human Kidney |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05%BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | L1CAM |
| 全名 | L1 Cell Adhesion Molecule |
| 背景介绍 | The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013] |
| 生物功能 | Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity. [Uniprot] |
| 细胞定位 | Cell membrane, Cell projection, Membrane |
| 预测分子量 | 140 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG67039 anti-L1CAM antibody [SQab30319] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded human Kidney stained with ARG67039 anti-L1CAM antibody [SQab30319].
