ARG64246
anti-Ku 70 antibody
anti-Ku 70 antibody for Western blot and Human
Cancer antibody; Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes Ku 70 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Ku 70 |
| 抗原物种 | Human |
| 抗原 | YKTEGDEEAEEEQ-C |
| 偶联标记 | Un-conjugated |
| 別名 | DNA repair protein XRCC6; Thyroid-lupus autoantigen; Lupus Ku autoantigen protein p70; EC 4.2.99.-; EC 3.6.4.-; ATP-dependent DNA helicase II 70 kDa subunit; X-ray repair complementing defective repair in Chinese hamster cells 6; CTC box-binding factor 75 kDa subunit; 70 kDa subunit of Ku antigen; CTC75; 5'-deoxyribose-5-phosphate lyase Ku70; KU70; TLAA; 5'-dRP lyase Ku70; CTCBF; ML8; G22P1; X-ray repair cross-complementing protein 6; ATP-dependent DNA helicase 2 subunit 1; Ku70 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P12956 Human X-ray repair cross-complementing protein 6 |
|---|---|
| 背景介绍 | The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008] |
| 研究领域 | Cancer antibody; Gene Regulation antibody |
| 预测分子量 | 70 kDa |
| 翻译后修饰 | Phosphorylation by PRKDC may enhance helicase activity. Phosphorylation of Ser-51 does not affect DNA repair. |
检测图片 (2) Click the Picture to Zoom In
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ARG64246 anti-Ku 70 antibody WB image
Western blot: HeLa cell lysate (35 µg protein in RIPA buffer) stained with ARG64246 anti-Ku 70 antibody at 0.1 µg/ml dilution.
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ARG64246 anti-Ku 70 antibody WB image
Western blot: 1). Mock transfection; 2) KU70 (RC204048) expressing plasmid transfected HEK293 cell lysate standed with ARG64246 anti-Ku 70 antibody.
