ARG24151
anti-Kir2.1 / KCNJ2 antibody [S112]
anti-Kir2.1 / KCNJ2 antibody [S112] for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey
概述
| 产品描述 | Mouse Monoclonal antibody [S112] recognizes Kir2.1 / KCNJ2 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Mk |
| 应用 | ICC/IF, IHC-P, WB |
| 特异性 | ~45kDa. No cross-reactivity against Kir2.2 or Kir2.3. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | S112 |
| 同位型 | IgG1 |
| 靶点名称 | Kir2.1 / KCNJ2 |
| 抗原物种 | Mouse |
| 抗原 | Fusion protein amino acids 41-64 and 189-428 of mouse Kir2.1 |
| 偶联标记 | Un-conjugated |
| 別名 | KCNJ2 ; Potassium Inwardly Rectifying Channel Subfamily J Member 2; IRK1; LQT7 Cardiac Inward Rectifier Potassium Channel; Inward Rectifier Potassium Channel 2; KIR2.1; IRK-1; HIRK1; Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 50% Glycerol and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KCNJ2 |
| 全名 | Potassium Inwardly Rectifying Channel Subfamily J Member 2 |
| 背景介绍 | Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. |
| 生物功能 | Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. |
| 细胞定位 | Membrane |
| 翻译后修饰 | Disulfide bond, Lipoprotein, Myristate, S-nitrosylation |
检测图片 (3) Click the Picture to Zoom In
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ARG24151 anti-Kir2.1 / KCNJ2 antibody [S112] IHC-P image
Immunohistochemistry: Mouse backskin stained with ARG24151 anti-Kir2.1 / KCNJ2 antibody [S112] at 1:100 dilution.
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ARG24151 anti-Kir2.1 / KCNJ2 antibody [S112] ICC/IF image
Immunofluorescence: SH-SY5Y stained with ARG24151 anti-Kir2.1 / KCNJ2 antibody [S112] at 1:50 dilution.
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ARG24151 anti-Kir2.1 / KCNJ2 antibody [S112] WB image
Western blot: COS stained with ARG24151 anti-Kir2.1 / KCNJ2 antibody [S112] at 1:1000 dilution.
