ARG40158
anti-KREMEN1 antibody
anti-KREMEN1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KREMEN1 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | IHC-P, WB |
| 特异性 | Three isoforms of KREMEN1 exists as a result of alternative splicing event. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KREMEN1 |
| 抗原物种 | Human |
| 抗原 | A 18 amino acid peptide within the last 50 amino acids of Human KREMEN1. |
| 偶联标记 | Un-conjugated |
| 別名 | KREMEN; KRM1; Dickkopf receptor; Kringle domain-containing transmembrane protein 1; Kremen protein 1; Kringle-containing protein marking the eye and the nose |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KREMEN1 |
| 全名 | kringle containing transmembrane protein 1 |
| 背景介绍 | This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 52 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG40158 anti-KREMEN1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human small intestine stained with ARG40158 anti-KREMEN1 antibody at 20 µg/ml dilution.
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ARG40158 anti-KREMEN1 antibody WB image
Western blot: Rat small intestine lysate stained with ARG40158 anti-KREMEN1 antibody at 0.125 µg/ml (left) and 0.25 µg/ml (right) dilution.
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ARG40158 anti-KREMEN1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human small intestine stained with ARG40158 anti-KREMEN1 antibody at 5 µg/ml dilution.
