ARG63494

anti-KMT2B / MLL4 antibody

anti-KMT2B / MLL4 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Gene Regulation antibody

概述

产品描述 Goat Polyclonal antibody recognizes KMT2B / MLL4
反应物种 Hu
预测物种 Ms, Rat, Dog, Pig
应用 IHC-P, WB
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 KMT2B / MLL4
抗原物种 Human
抗原 CNCGAKRCRRFLN
偶联标记 Un-conjugated
別名 TRX2; Trithorax homolog 2; HRX2; MLL1B; WW domain-binding protein 7; Histone-lysine N-methyltransferase 2B; Lysine N-methyltransferase 2B; MLL2; CXXC10; WBP-7; MLL4; EC 2.1.1.43; WBP7; Myeloid/lymphoid or mixed-lineage leukemia protein 4

应用说明

应用建议
应用 推荐稀释比
IHC-PAssay - dependent
WB5 - 10 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 9757 Human KMT2B

Swiss-port # Q9UMN6 Human Histone-lysine N-methyltransferase 2B

背景介绍 This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
研究领域 Gene Regulation antibody
预测分子量 294 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG63494 anti-KMT2B / MLL4 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human cortex tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63494 anti-KMT2B / MLL4 antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG63494 anti-MLL4 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Testis. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63494 anti-MLL4 antibody at 5 µg/ml dilution followed by AP-staining.