ARG59324
anti-KLK8 antibody
anti-KLK8 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KLK8 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KLK8 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein corresponding to V33-G260 of Human KLK8. |
| 偶联标记 | Un-conjugated |
| 別名 | PRSS19; NRPN; EC 3.4.21.118; Ovasin; hK8; HNP; TADG14; Tumor-associated differentially expressed gene 14 protein; NP; Kallikrein-8; Serine protease TADG-14; Serine protease 19; Neuropsin |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KLK8 |
| 全名 | kallikrein-related peptidase 8 |
| 背景介绍 | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] |
| 生物功能 | Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury. [UniProt] |
| 细胞定位 | Secreted. Cytoplasm. Note=Shows a cytoplasmic distribution in the keratinocytes. [UniProt] |
| 预测分子量 | 28 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59324 anti-KLK8 antibody WB image
Western blot: Human placenta stained with ARG59324 anti-KLK8 antibody at 0.5 µg/ml dilution.
