ARG45663
anti-KLK11 antibody
anti-KLK11 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KLK11 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KLK11 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to C-terminal region of human KLK11. |
| 偶联标记 | Un-conjugated |
| 別名 | KLK11; kallikrein-related peptidase 11; Trypsin-like protease; Kallikrein-11; hK11; PRSS20; EC 3.4.21.-; Serine protease 20; TLSP; Hippostasin |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 31 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KLK11 |
| 全名 | kallikrein-related peptidase 11 |
| 背景介绍 | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009] |
| 生物功能 | Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues. [UniProt] |
| 细胞定位 | Golgi apparatus; Secreted. [UniProt] |
| 预测分子量 | 31 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein; Zymogen. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG45663 anti-KLK11 antibody IHC-P image
Immunohistochemistry: Human prostatic cancer stained with ARG45663 anti-KLK11 antibody.
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ARG45663 anti-KLK11 antibody WB image
Western blot: U87 stained with ARG45663 anti-KLK11 antibody.
