ARG45637
anti-KLK1 / Kallikrein 1 antibody
anti-KLK1 / Kallikrein 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KLK1 / Kallikrein 1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KLK1 / Kallikrein 1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to middle region of human KLK1 / Kallikrein 1. |
| 偶联标记 | Un-conjugated |
| 別名 | KLK1; Kallikrein 1; Klk6; Kidney/Pancreas/Salivary Gland Kallikrein; Kallikrein 1, Renal/Pancreas/Salivary; Tissue Kallikrein; Kallikrein-1; EC 3.4.21.35 47; Kallikrein Serine Protease 1; Glandular Kallikrein 1; EC 3.4.21 47; KLKR; HK1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 29 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KLK1 |
| 全名 | Kallikrein 1 |
| 背景介绍 | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008 |
| 生物功能 | Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. ( KLK1_HUMAN,P06870 ) (Microbial infection) Cleaves Neisseria meningitidis NHBA in saliva; Neisseria is an obligate commensal of the nasopharyngeal mucosa. [UniProt] |
| 细胞定位 | extracellular exosome. [UniProt] |
| 预测分子量 | 29 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein; Zymogen. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45637 anti-KLK1 / Kallikrein 1 antibody IHC-P image
Immunohistochemistry: Human pancreatic cancer stained with ARG45637 anti-KLK1 / Kallikrein 1 antibody at 2 μg/ml dilution.
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ARG45637 anti-KLK1 / Kallikrein 1 antibody WB image
Western blot: Rat pancreas stained with ARG45637 anti-KLK1 / Kallikrein 1 antibody at 0.5 μg/ml dilution.
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ARG45637 anti-KLK1 / Kallikrein 1 antibody WB image
Western blot: Mouse pancreas stained with ARG45637 anti-KLK1 / Kallikrein 1 antibody at 0.5 μg/ml dilution.
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ARG45637 anti-KLK1 / Kallikrein 1 antibody WB image
Western blot: KLK1 / Kallikrein 1 recombinant protein stained with ARG45637 anti-KLK1 / Kallikrein 1 antibody at 0.5 μg/ml dilution.
