ARG54000
anti-KLF4 antibody
anti-KLF4 antibody for Western blot and Mouse
Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody; Gene Regulation antibody
概述
| 产品描述 | Mouse Monoclonal antibody recognizes KLF4 |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | KLF4 |
| 抗原物种 | Mouse |
| 抗原 | Purified recombinant mouse KLF4 protein fragments expressed in E.coli. |
| 偶联标记 | Un-conjugated |
| 別名 | GKLF; EZF; Epithelial zinc finger protein EZF; Krueppel-like factor 4; Gut-enriched krueppel-like factor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 55/65 kDa |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | Ascites |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Klf4 |
| 全名 | Kruppel-like factor 4 (gut) |
| 背景介绍 | Transcription factor; can act both as activator and as repressor.Binds the 5'-CACCC-3' core sequence.Binds to the promoter region of its own gene and can activate its own transcription.Regulates the expression of key transcription factors during embryonic development.Plays an important role in maintaining embryonic stem cells,and in preventing their differentiation.Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface.Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.Contributes to the down-regulation of p53/TP53 transcription. |
| 生物功能 | Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription (By similarity). [UniProt] |
| 细胞定位 | Nucleus. |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody; Gene Regulation antibody |
| 预测分子量 | 55 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG54000 anti-KLF4 antibody WB image
Western blot: CHO-K1 cells transfected with pDNA3.1-Hygro(+)-Flag vector (left) or pcDNA3.1-Hygro(+)-mKLF4-Flag (right). The blots were stained with ARG54000 anti-KLF4 antibody at 1:1000 dilution.
