ARG46240
anti-KIRREL2 antibody
anti-KIRREL2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KIRREL2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KIRREL2 |
| 抗原物种 | Human |
| 抗原 | A 17 amino acid synthetic peptide within aa. 550 - 600 of human KIRREL2. |
| 偶联标记 | Un-conjugated |
| 別名 | KIRREL2; kin of IRRE like 2 (Drosophila); Kin of irregular chiasm-like protein 2; Kin of IRRE-like protein 2; NEPH3; Nephrin-like protein 3; NLG1; FILTRIN |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 70 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -290°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KIRREL2 |
| 全名 | kin of IRRE like 2 (Drosophila) |
| 背景介绍 | This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016] |
| 生物功能 | May regulate basal insulin secretion. [UniProt] |
| 细胞定位 | Cell membrane. [UniProt] |
| 预测分子量 | 64, 70, 78 kDa |
| 翻译后修饰 | Phosphoprotein; Disulfide bond; Glycoprotein. [UniProt] |
