ARG43028
anti-KIF5B / Kinesin Heavy Chain antibody
anti-KIF5B / Kinesin Heavy Chain antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KIF5B / Kinesin Heavy Chain |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KIF5B / Kinesin Heavy Chain |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 650-770 of Human KIF5B / Kinesin Heavy Chain (NP_004512.1). |
| 偶联标记 | Un-conjugated |
| 別名 | HEL-S-61; Kinesin-1 heavy chain; Conventional kinesin heavy chain; KINH; KNS1; Ubiquitous kinesin heavy chain; UKHC; KNS |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HeLa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KIF5B |
| 全名 | kinesin family member 5B |
| 生物功能 | Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity). Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity). [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton. Note=Uniformly distributed between soma and neurites in hippocampal neurons. [UniProt] |
| 预测分子量 | 110 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG43028 anti-KIF5B / Kinesin Heavy Chain antibody ICC/IF image
Immunofluorescence: C6 cells stained with ARG43028 anti-KIF5B / Kinesin Heavy Chain antibody at 1:100 dilution.
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ARG43028 anti-KIF5B / Kinesin Heavy Chain antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse lung tissue stained with ARG43028 anti-KIF5B / Kinesin Heavy Chain antibody at 1:200 dilution.
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ARG43028 anti-KIF5B / Kinesin Heavy Chain antibody WB image
Western blot: 25 µg of HeLa cell lysate stained with ARG43028 anti-KIF5B / Kinesin Heavy Chain antibody at 1:1000 dilution.
