ARG41241
anti-KIF23 / MKLP1 antibody
anti-KIF23 / MKLP1 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KIF23 / MKLP1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KIF23 / MKLP1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human KIF23 / MKLP1. |
| 偶联标记 | Un-conjugated |
| 別名 | MKLP-1; MKLP1; Mitotic kinesin-like protein 1; CHO1; KNSL5; Kinesin-like protein 5; Kinesin-like protein KIF23 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 110 kDa; 98 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KIF23 |
| 全名 | kinesin family member 23 |
| 背景介绍 | The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| 生物功能 | Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody, Midbody ring. Note=Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis. [UniProt] |
| 预测分子量 | Isoform 1: 110 kDa Isoform 2: 98 kDa |
| 翻译后修饰 | Ubiquitinated. Deubiquitinated by USP8/UBPY. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG41241 anti-KIF23 / MKLP1 antibody WB image
Western blot: HeLa cell lysate stained with ARG41241 anti-KIF23 / MKLP1 antibody.
