ARG43239
anti-KIF21B antibody
anti-KIF21B antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KIF21B |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KIF21B |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human KIF21B. |
| 偶联标记 | Un-conjugated |
| 別名 | Kinesin-like protein KIF21B |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | WB: Mouse brain IHC-P: Human colorectal cancer tissue |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 40% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KIF21B |
| 全名 | kinesin family member 21B |
| 背景介绍 | This gene encodes a member of the kinesin superfamily. Kinesins are ATP-dependent microtubule-based motor proteins that are involved in the intracellular transport of membranous organelles. Single nucleotide polymorphisms in this gene are associated with inflammatory bowel disease and multiple sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
| 生物功能 | Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface. [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton. Cell projection, dendrite. Cell projection, growth cone. Cell projection, axon. Cytoplasmic vesicle. [UniProt] |
| 预测分子量 | 183 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG43239 anti-KIF21B antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human colorectal cancer tissue stained with ARG43239 anti-KIF21B antibody (left) at 1:40 dilution, or the same antibody pre-incubated with synthetic peptide (right). (Original magnification: X200).
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ARG43239 anti-KIF21B antibody WB image
Western blot: 40 µg of Mouse brain lysate stained with ARG43239 anti-KIF21B antibody at 1:1000 dilution.
