ARG43218
anti-KIF20B antibody
anti-KIF20B antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KIF20B |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KIF20B |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1200-1500 of Human KIF20B (NP_057279.2). |
| 偶联标记 | Un-conjugated |
| 別名 | MPP-1; MPHOSPH1; MPP1; KRMP1; Kinesin-related motor interacting with PIN1; M-phase phosphoprotein 1; Kinesin-like protein KIF20B; Cancer/testis antigen 90; CT90 |
应用说明
| 预测反应性说明 | Mouse, Rat | ||||
|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | U-251MG | ||||
| 实际分子量 | ~ 250 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KIF20B |
| 全名 | kinesin family member 20B |
| 生物功能 | Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Midbody. Cell projection, axon. Cell projection, growth cone. [UniProt] |
| 预测分子量 | 211 kDa |
| 翻译后修饰 | Phosphorylated during mitosis by CDK1 (PubMed:11470801, PubMed:12740395). [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG43218 anti-KIF20B antibody WB image
Western blot: 25 µg of U-251MG cell lysate stained with ARG43218 anti-KIF20B antibody at 1:1000 dilution.
