ARG59552

anti-KDM6B / JMJD3 antibody

anti-KDM6B / JMJD3 antibody for ICC/IF,Western blot and Human

概述

产品描述 Rabbit Polyclonal antibody recognizes KDM6B / JMJD3
反应物种 Hu
预测物种 Ms, Rat
应用 ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 KDM6B / JMJD3
抗原物种 Human
抗原 A 16 aa peptide within aa. 1370 - 1420 of Human KDM6B / JMJD3.
偶联标记 Un-conjugated
別名 JmjC domain-containing protein 3; Lysine-specific demethylase 6B; JMJD3; Lysine demethylase 6B; Jumonji domain-containing protein 3; EC 1.14.11.-

应用说明

应用建议
应用 推荐稀释比
ICC/IF2.5 - 5 µg/ml
WB0.5 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 K562 Cell Lysate

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS and 0.02% Sodium azide
抗菌剂 0.02% Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 23135 Human KDM6B

Swiss-port # O15054 Human Lysine-specific demethylase 6B

基因名称 KDM6B
全名 lysine (K)-specific demethylase 6B
生物功能 Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. [UniProt]
细胞定位 Nucleus. [UniProt]
预测分子量 177 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG59552 anti-KDM6B / JMJD3 antibody ICC/IF image

    Immunofluorescence: K562 cells stained with ARG59552 anti-KDM6B / JMJD3 antibody at 20 µg/ml dilution.

  • ARG59552 anti-KDM6B / JMJD3 antibody WB image

    Western blot: HeLa cell lysate stained with ARG59552 anti-KDM6B / JMJD3 antibody at 0.25 µg/ml dilution.