ARG59524
anti-KDM6B / JMJD3 antibody
anti-KDM6B / JMJD3 antibody for ICC/IF,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KDM6B / JMJD3 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KDM6B / JMJD3 |
| 抗原物种 | Mouse |
| 抗原 | Recombinant fusion protein corresponding to aa. 90-190 of Mouse KDM6B / JMJD3 (NP_001017426.1). |
| 偶联标记 | Un-conjugated |
| 別名 | JmjC domain-containing protein 3; Lysine-specific demethylase 6B; JMJD3; Lysine demethylase 6B; Jumonji domain-containing protein 3; EC 1.14.11.- |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | SH-SY5Y | ||||||
| 实际分子量 | 170 - 180 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KDM6B |
| 全名 | lysine (K)-specific demethylase 6B |
| 生物功能 | Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 177 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG59524 anti-KDM6B / JMJD3 antibody ICC/IF image
Immunofluorescence: NIH/3T3 cells stained with ARG59524 anti-KDM6B / JMJD3 antibody at 1:100 dilution.
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ARG59524 anti-KDM6B / JMJD3 antibody WB image
Western blot: 25 µg of SH-SY5Y cell lysates stained with ARG59524 anti-KDM6B / JMJD3 antibody at 1:3000 dilution.
