ARG46222
anti-KDM3B / JMJD1B antibody
anti-KDM3B / JMJD1B antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KDM3B / JMJD1B |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KDM3B / JMJD1B |
| 抗原物种 | Human |
| 抗原 | A 20 amino acid synthetic peptide within aa. 1050 - 1100 of human KDM3B / JMJD1B . |
| 偶联标记 | Un-conjugated |
| 別名 | KDM3B; lysine (K)-specific demethylase 3B; JMJD1B; 5qNCA; NET22; C5orf7; JMJD1B; JHDM2B; KIAA1082; Lysine-specific demethylase 3B; JmjC domain-containing histone demethylation protein 2B |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -272°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KDM3B |
| 全名 | lysine (K)-specific demethylase 3B |
| 背景介绍 | Predicted to enable chromatin DNA binding activity; histone H3K9 demethylase activity; and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. Biomarker of acute lymphoblastic leukemia; breast cancer; colorectal cancer; and lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 192 kDa |
| 翻译后修饰 | Phosphoprotein; Isopeptide bond; Ubl conjugation; Acetylation. [UniProt] |
