ARG65085

anti-KCNN2 antibody

anti-KCNN2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Neuroscience antibody

概述

产品描述 Goat Polyclonal antibody recognizes KCNN2
反应物种 Hu
预测物种 Ms, Rat, Cow, Dog
应用 IHC-P, WB
特异性 This antibody is expected to recognize both isoforms (NP_067627.2; NP_740721.1).
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 KCNN2
抗原物种 Human
抗原 C-ESYDKHVTYNAER
偶联标记 Un-conjugated
別名 KCa2.2; SK2; hSK2; SKCA2; Small conductance calcium-activated potassium channel protein 2; SKCa2; SKCa 2

应用说明

应用建议
应用 推荐稀释比
IHC-P3 - 5 µg/ml
WB0.3 - 1 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 3781 Human KCNN2

Swiss-port # Q9H2S1 Human Small conductance calcium-activated potassium channel protein 2

背景介绍 Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
研究领域 Neuroscience antibody
预测分子量 64 kDa

检测图片 (3) Click the Picture to Zoom In

  • ARG65085 anti-KCNN2 antibody WB image

    Western Blot: Human Liver lysate (35 µg protein in RIPA buffer) stained with ARG65085 anti-KCNN2 antibody at 0.3 µg/ml dilution.

  • ARG65085 anti-KCNN2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG65085 anti-KCNN2 antibody at 3.75 µg/ml dilution followed by AP-staining.

  • ARG65085 anti-KCNN2 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Thyroid Gland. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG65085 anti-KCNN2 antibody at 3.8 µg/ml dilution followed by AP-staining.