ARG40337
anti-KCNJ5 / GIRK4 antibody
anti-KCNJ5 / GIRK4 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KCNJ5 / GIRK4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KCNJ5 / GIRK4 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within aa. 50-150 of Human KCNJ5 (NP_000881.3). |
| 偶联标记 | Un-conjugated |
| 別名 | GIRK-4; IRK-4; LQT13; KIR3.4; Heart KATP channel; KATP-1; KATP1; CIR; Inward rectifier K; Cardiac inward rectifier; Potassium channel, inwardly rectifying subfamily J member 5; GIRK4; G protein-activated inward rectifier potassium channel 4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Rat heart | ||||
| 实际分子量 | 42 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KCNJ5 |
| 全名 | potassium channel, inwardly rectifying subfamily J, member 5 |
| 背景介绍 | Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008] |
| 生物功能 | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. [UniProt] |
| 细胞定位 | Membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 48 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG40337 anti-KCNJ5 / GIRK4 antibody WB image
Western blot: 25 µg of Rat heart lysate stained with ARG40337 anti-KCNJ5 / GIRK4 antibody at 1:1000 dilution.
