ARG11173
anti-KCNIP4 antibody
anti-KCNIP4 antibody for Western blot and Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KCNIP4 |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KCNIP4 |
| 抗原物种 | Mouse |
| 抗原 | A synthetic peptide (KTSSPAIQNSV) derived from the amino sequence acid residue 45-57 of mouse Kchip4, conjugated with KLH for immunization. |
| 偶联标记 | Un-conjugated |
| 別名 | KCNIP4; Potassium Voltage-Gated Channel Interacting Protein 4; KCHIP4; CALP; A-Type Potassium Channel Modulatory Protein 4; Kv Channel Interacting Protein 4; Kv Channel-Interacting Protein 4; Calsenilin-Like Protein; MGC44947; Potassium Channel-Interacting Protein 4; KChIP4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G affinity purified |
| 缓冲液 | 0.01M PBS (pH 7.4) |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KCNIP4 |
| 全名 | Potassium Voltage-Gated Channel Interacting Protein 4 |
| 背景介绍 | This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane. [UniProt] |
| 细胞定位 | Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane, Peroxisome. [UniProt] |
| 预测分子量 | 29 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
