ARG66452
anti-KCNC4 / Kv3.4 antibody
anti-KCNC4 / Kv3.4 antibody for Western blot and Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KCNC4 / Kv3.4 |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KCNC4 / Kv3.4 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide within the N-terminal region of Human KCNC4 / Kv3.4. |
| 偶联标记 | Un-conjugated |
| 別名 | C1orf30; KSHIIIC; Potassium voltage-gated channel subfamily C member 4; HKSHIIIC; Voltage-gated potassium channel subunit Kv3.4; KV3.4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q63734 Rat Potassium voltage-gated channel subfamily C member 4 |
|---|---|
| 基因名称 | KCNC4 |
| 全名 | potassium channel, voltage gated Shaw related subfamily C, member 4 |
| 背景介绍 | The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010] |
| 生物功能 | This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. [UniProt] |
| 细胞定位 | Membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 70 kDa |
| 翻译后修饰 | Phosphorylation of serine residues in the inactivation gate inhibits rapid channel closure. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG66452 anti-KCNC4 / Kv3.4 antibody WB image
Western blot: Rat brain whole cell lysate stained with ARG66452 anti-KCNC4 / Kv3.4 antibody.
