ARG64351
anti-KCC3 / SLC12A6 antibody
anti-KCC3 / SLC12A6 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes KCC3 / SLC12A6 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 特异性 | This antibody is expected to recognise all 6 reported isofoms (NP_598408.1; NP_005126.1; NP_001035959.1; NP_001035960.1; NP_001035961.1; NP_001035962.1; ); |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KCC3 / SLC12A6 |
| 抗原物种 | Human |
| 抗原 | SRHIDVCSKTKE |
| 偶联标记 | Un-conjugated |
| 別名 | ACCPN; K-Cl cotransporter 3; Electroneutral potassium-chloride cotransporter 3; Solute carrier family 12 member 6; KCC3A; KCC3B; KCC3 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008] |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 128 kDa |
| 翻译后修饰 | N-glycosylated. |
检测图片 (2) Click the Picture to Zoom In
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ARG64351 anti-KCC3 / SLC12A6 antibody WB image
Western Blot: Human Heart lysate (35 µg protein in RIPA buffer) stained with ARG64351 anti-KCC3 / SLC12A6 antibody at 0.1 µg/ml dilution.
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ARG64351 anti-KCC3 / SLC12A6 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Heart. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64351 anti-KCC3 / SLC12A6 antibody at 2.5 µg/ml dilution followed by AP-staining.
