ARG46232
anti-KANK1 antibody
anti-KANK1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KANK1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KANK1 |
| 抗原物种 | Human |
| 抗原 | A 19 amino acid synthetic peptide within the first 50 amino acids of human KANK1. |
| 偶联标记 | Un-conjugated |
| 別名 | KN motif and ankyrin repeat domains 1; KANK1; KANK; CPSQ2; ANKRD15; KANK; KIAA0172; KN motif and ankyrin repeat domain-containing protein 1; Ankyrin repeat domain-containing protein 15 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 150 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -282°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q14678 Human KN motif and ankyrin repeat domain-containing protein 1 |
|---|---|
| 基因名称 | KANK1 |
| 全名 | KN motif and ankyrin repeat domains 1 |
| 背景介绍 | The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2014] |
| 生物功能 | Adapter protein that links structural and signaling protein complexes positioned to guide microtubule and actin cytoskeleton dynamics during cell morphogenesis. [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus; Cell projection. [UniProt] |
| 预测分子量 | 149 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
