ARG56873
anti-Jagged 1 antibody [J1G53-3]
anti-Jagged 1 antibody [J1G53-3] for Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [J1G53-3] recognizes Jagged 1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | J1G53-3 |
| 同位型 | IgG1, kappa |
| 靶点名称 | Jagged 1 |
| 抗原物种 | Human |
| 抗原 | Recombinant Human Jagged1. |
| 偶联标记 | Un-conjugated |
| 別名 | Protein jagged-1; HJ1; AHD; Jagged1; AWS; CD antigen CD339; CD339; JAGL1; hJ1; AGS |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | 0.2 µm filtered. |
| 缓冲液 | PBS (pH 7.4) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | JAG1 |
| 全名 | jagged 1 |
| 背景介绍 | The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro). [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein |
| 预测分子量 | 134 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG56873 anti-Jagged 1 antibody [J1G53-3] WB image
Western blot: 1) Human Jagged-1 Fc fusion proteion, 2) Human Jagged-1 transfected 293 cell lysate and 3) Mock transfected 293 cell lysate stained with ARG56873 anti-Jagged 1 antibody [J1G53-3] at 1:1000 dilution.
