ARG65984
anti-Jagged 1 antibody
anti-Jagged 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Jagged 1 |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Jagged 1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the internal region of Human Jagged1. |
| 偶联标记 | Un-conjugated |
| 別名 | Protein jagged-1; HJ1; AHD; Jagged1; AWS; CD antigen CD339; CD339; JAGL1; hJ1; AGS |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | JAG1 |
| 全名 | jagged 1 |
| 背景介绍 | The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro). [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein |
| 预测分子量 | 134 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG65984 anti-Jagged 1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse kidney tissue stained with ARG65984 anti-Jagged 1 antibody at 1:100 dilution.
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ARG65984 anti-Jagged 1 antibody WB image
Western blot: HeLa cells stained with ARG65984 anti-Jagged 1 antibody.
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ARG65984 anti-Jagged 1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse kidney tissue stained with ARG65984 anti-Jagged 1 antibody at 1:100 dilution.
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ARG65984 anti-Jagged 1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse kidney tissue stained with ARG65984 anti-Jagged 1 antibody at 1:100 dilution.
