ARG46231

anti-JP-4 antibody

anti-JP-4 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes JP-4
反应物种 Hu, Ms, Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 JP-4
抗原物种 Human
抗原 A 16 amino acid synthetic peptide within aa. 530 - 580 of human JP-4.
偶联标记 Un-conjugated
別名 junctophilin 4; JPH4; JP4; JPHL1; KIAA1831; Junctophilin-4; Junctophilin-like 1 protein; JP-4

应用说明

应用建议
应用 推荐稀释比
IHC-PAssay-dependent
WBAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity chromatography purified
缓冲液 PBS and 0.02% Sodium azide.
抗菌剂 0.02% Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -281°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 319984 Mouse JPH4

GeneID: 445271 Rat JPH4

GeneID: 84502 Human JPH4

基因名称 JPH4
全名 junctophilin 4
背景介绍 This gene encodes a member of the junctophilin family of transmembrane proteins that are involved in the formation of the junctional membrane complexes between the plasma membrane and the endoplasmic/sarcoplasmic reticulum in excitable cells. The encoded protein contains a conserved N-terminal repeat region called the membrane occupation and recognition nexus sequence that is found in other members of the junctophilin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
生物功能 Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory (By similarity). [UniProt]
细胞定位 Cell membrane ; Endoplasmic reticulum membrane. [UniProt]
预测分子量 66 kDa