ARG46223
anti-JMJD1C antibody
anti-JMJD1C antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes JMJD1C |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | JMJD1C |
| 抗原物种 | Human |
| 抗原 | A 20 amino acid synthetic peptide within aa. 380 - 430 of human JMJD1C. |
| 偶联标记 | Un-conjugated |
| 別名 | JMJD1C; TRIP-8; TR-interacting protein 8; Jumonji domain-containing protein 1C; Thyroid receptor-interacting protein 8; TRIP8; EC 1.14.11.-; Probable JmjC domain-containing histone demethylation protein 2C |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 纯化 | Affinity chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q15652 Human Probable JmjC domain-containing histone demethylation protein 2C Swiss-port # Q69ZK6 Mouse Probable JmjC domain-containing histone demethylation protein 2C |
|---|---|
| 基因名称 | JMJD1C |
| 全名 | jumonji domain containing 1C |
| 背景介绍 | JMJD1C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD1C has been identified as a nuclear-receptor coactivator and is a candidate gene for autism. |
| 生物功能 | Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity). [UniProt] |
