ARG63322
anti-JIP3 / Syd 2 / JSAP1 antibody
anti-JIP3 / Syd 2 / JSAP1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Mouse
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes JIP3 / Syd 2 / JSAP1 |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Hu, Rat, Cow |
| 应用 | IHC-P |
| 特异性 | This antibody is expected to recognise both reported Human isoforms of this protein (as represented by NP_055948.2 and NP_001035529.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | JIP3 / Syd 2 / JSAP1 |
| 抗原物种 | Human |
| 抗原 | MEIQMDEGGGVV-C |
| 偶联标记 | Un-conjugated |
| 別名 | JIP-3; Mitogen-activated protein kinase 8-interacting protein 3; syd; JIP3; JNK MAP kinase scaffold protein 3; JNK-interacting protein 3; JSAP1; C-Jun-amino-terminal kinase-interacting protein 3; SYD2 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9ESN9 Mouse C-Jun-amino-terminal kinase-interacting protein 3 |
|---|---|
| 背景介绍 | The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 147 kDa |
| 翻译后修饰 | Phosphorylation by ROCK1 is crucial for the recruitment of JNK. |
检测图片 (1) Click the Picture to Zoom In
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ARG63322 anti-JIP3 / Syd 2 / JSAP1 antibody IHC-P image
Immunohistochemistry: Paraffin embedded Mouse Brain. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63322 anti-JIP3 / Syd 2 / JSAP1 antibody at 4 µg/ml dilution followed by HRP-staining.
