ARG63623
anti-JIK / TAOK3 antibody
anti-JIK / TAOK3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Gene Regulation antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes JIK / TAOK3 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | JIK / TAOK3 |
| 抗原物种 | Human |
| 抗原 | CHKKDHVFIRDEAGHGD |
| 偶联标记 | Un-conjugated |
| 別名 | JNK/SAPK-inhibitory kinase; Jun kinase-inhibitory kinase; hKFC-A; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; JIK; Dendritic cell-derived protein kinase; Kinase from chicken homolog A; Thousand and one amino acid protein 3; MAP3K18; EC 2.7.11.1; Serine/threonine-protein kinase TAO3; DPK; CTCL-associated antigen HD-CL-09 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9H2K8 Human Serine/threonine-protein kinase TAO3 |
|---|---|
| 基因名称 | TAOK3 |
| 全名 | TAO kinase 3 |
| 生物功能 | Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF). [UniProt] |
| 研究领域 | Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 105 kDa |
| 翻译后修饰 | Autophosphorylated. Phosphorylation at Ser-324 by ATM following DNA damage is required for activation of the p38/MAPK14 stress-activated MAPK cascade. Phosphorylated by LRRK2. |
检测图片 (2) Click the Picture to Zoom In
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ARG63623 anti-JIK / TAOK3 antibody WB image
Western Blot: human liver lysate (35 µg protein in RIPA buffer) stained with ARG63623 anti-JIK / TAOK3 antibody at 0.1 µg/ml dilution.
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ARG63623 anti-JIK / TAOK3 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Prostate. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63623 anti-JIK / TAOK3 antibody at 2.5 µg/ml dilution followed by AP-staining.
