ARG41948
anti-JAZF1 antibody
anti-JAZF1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes JAZF1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog, Gpig, Hrs, Rb, Zfsh |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | JAZF1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the C-terminal region of Human JAZF1. (within the following region: KKRYK NVNGI KYHAK NGHRT QIRVR KPFKC RCGKS YKTAQ GLRHH TINFH) |
| 偶联标记 | Un-conjugated |
| 別名 | TAK1-interacting protein 27; Zinc finger protein 802; Juxtaposed with another zinc finger protein 1; ZNF802; TIP27 |
应用说明
| 预测反应性说明 | Predicted Homology Based On Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea pig: 100%; Horse: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% | ||||||
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| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | 293T whole cell | ||||||
| 实际分子量 | ~ 29 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q86VZ6 Human Juxtaposed with another zinc finger protein 1 |
|---|---|
| 基因名称 | JAZF1 |
| 全名 | JAZF zinc finger 1 |
| 背景介绍 | This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008] |
| 生物功能 | Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2. Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity (By similarity). Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD (By similarity). Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue (By similarity). Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity (By similarity). [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 27 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG41948 anti-JAZF1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human testis tissue stained with ARG41948 anti-JAZF1 antibody at 5 µg/ml dilution.
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ARG41948 anti-JAZF1 antibody WB image
Western blot: 293T whole cell lysate stained with ARG41948 anti-JAZF1 antibody at 1 µg/ml dilution.
