ARG45730
anti-J Chain antibody
anti-J Chain antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes J Chain |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | J Chain |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human J Chain. |
| 偶联标记 | Un-conjugated |
| 別名 | JCHAIN; Joining chain of multimeric IgA and IgM; Immunoglobulin J chain; IGCJ; JCH; IGJ |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 23 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | JCHAIN |
| 全名 | joining chain of multimeric IgA and IgM |
| 背景介绍 | Enables IgA binding activity and protein homodimerization activity. Contributes to several functions, including immunoglobulin receptor binding activity; peptidoglycan binding activity; and phosphatidylcholine binding activity. Involved in several processes, including glomerular filtration; innate immune response; and positive regulation of respiratory burst. Located in extracellular space. Part of monomeric IgA immunoglobulin complex; pentameric IgM immunoglobulin complex; and secretory dimeric IgA immunoglobulin complex. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 18 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein; Pyrrolidone carboxylic acid. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45730 anti-J Chain antibody IHC-P image
Immunohistochemistry: Human thyroid cancer stained with ARG45730 anti-J Chain antibody at 2 μg/ml dilution.
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ARG45730 anti-J Chain antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45730 anti-J Chain antibody at 5 μg/ml dilution.
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ARG45730 anti-J Chain antibody WB image
Western blot: Rat small intestine stained with ARG45730 anti-J Chain antibody at 0.5 μg/ml dilution.
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ARG45730 anti-J Chain antibody FACS image
Flow Cytometry: A431 stained with ARG45730 anti-J Chain antibody at 1 µg/10^6 cells dilution.
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ARG45730 anti-J Chain antibody IHC-P image
Immunohistochemistry: Rat colon stained with ARG45730 anti-J Chain antibody at 2 μg/ml dilution.
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ARG45730 anti-J Chain antibody WB image
Western blot: Mouse spleen stained with ARG45730 anti-J Chain antibody at 0.5 μg/ml dilution.
