ARG59359
anti-Involucrin antibody
anti-Involucrin antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Involucrin |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Involucrin |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human Involucrin. |
| 偶联标记 | Un-conjugated |
| 別名 | Involucrin |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | A431 | ||||||||
| 实际分子量 | 120 ~ 130 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IVL |
| 全名 | involucrin |
| 背景介绍 | Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008] |
| 生物功能 | Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. [UniProt] |
| 细胞定位 | Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope. [UniProt] |
| 预测分子量 | 68 kDa |
| 翻译后修饰 | Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG59359 anti-Involucrin antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human tonsil stained with ARG59359 anti-Involucrin antibody.
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ARG59359 anti-Involucrin antibody WB image
Western blot: A431 cell lysate stained with ARG59359 anti-Involucrin antibody.
