ARG22707
anti-Integrin alpha E2 antibody [OX-62] (PE)
anti-Integrin alpha E2 antibody [OX-62] (PE) for Flow cytometry and Rat
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [OX-62] recognizes Integrin alpha E2 This antibody recognizes OX-62 antigen, shown to be Rat alpha E2 integrin which is expressed by dendritic cells of dendritic epidermal T cells, intraepithelial lymphocytes in the small intestine and by cells of dendritic morphology in lymphoid organs, at sites where gamma delta T cells are present. |
|---|---|
| 反应物种 | Rat |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | OX-62 |
| 同位型 | IgG1 |
| 靶点名称 | Integrin alpha E2 |
| 抗原物种 | Rat |
| 抗原 | Density gradient enriched PVG rat thoracic duct dendritic cells. |
| 偶联标记 | PE |
| 別名 | CD103; HUMINAE; Integrin alpha-E; Mucosal lymphocyte 1 antigen; CD antigen CD103; HML-1 antigen; Integrin alpha-IEL |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.09% Sodium azide, 1% BSA and 5% Sucrose. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA and 5% Sucrose |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | ITGAE |
|---|---|
| 全名 | integrin, alpha E |
| 背景介绍 | Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008] |
| 生物功能 | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. [UniProt] |
| 预测分子量 | 130 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG22707 anti-Integrin alpha E2 antibody [OX-62] (PE) FACS image
Flow Cytometry: Rat splenocytes stained with ARG22707 anti-Integrin alpha E2 antibody [OX-62] (PE) in red filled, stained with Mouse IgG1 isotype control (PE) in blue line.
