ARG62518
anti-IgD antibody [IgD26]
anti-IgD 抗体 [IgD26] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Developmental Biology antibody; Immune System antibody
概述
| 产品描述 | Mouse Monoclonal antibody [IgD26] recognizes IgD |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | IgD26 |
| 同位型 | IgG1 |
| 靶点名称 | IgD |
| 抗原物种 | Human |
| 抗原 | IgD purified from human myeloma serum |
| 偶联标记 | Un-conjugated |
应用说明
| 应用说明 | WB: 1/100 - 1/1000 IP: 1-2 μl/mg of lysate IF: 1/50-1/500 IHC: 1/50-1/500 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS, < 0.1% Sodium azide and 0.1% Gelatin |
| 抗菌剂 | < 0.1% Sodium azide |
| 稳定剂 | 0.1% Gelatin |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | IGHD |
|---|---|
| 全名 | immunoglobulin heavy constant delta |
| 生物功能 | IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. [UniProt] |
| 研究领域 | Developmental Biology antibody; Immune System antibody |
