ARG58886
anti-ITPR3 / IP3R3 antibody
anti-ITPR3 / IP3R3 antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ITPR3 / IP3R3 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ITPR3 / IP3R3 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1630-1870 of Human ITPR3 / IP3R3 (NP_002215.2). |
| 偶联标记 | Un-conjugated |
| 別名 | IP3R; Type 3 inositol 1,4,5-trisphosphate receptor; Inositol 1,4,5-trisphosphate receptor type 3; Type 3 InsP3 receptor; InsP3R3; IP3R 3; IP3 receptor isoform 3; IP3R3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | LO2 | ||||||||
| 实际分子量 | 280 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P70227 Mouse Inositol 1,4,5-trisphosphate receptor type 3 Swiss-port # Q14573 Human Inositol 1,4,5-trisphosphate receptor type 3 |
|---|---|
| 基因名称 | ITPR3 |
| 全名 | inositol 1,4,5-trisphosphate receptor, type 3 |
| 背景介绍 | This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010] |
| 生物功能 | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane, Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 304 kDa |
| 翻译后修饰 | Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues (By similarity). [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG58886 anti-ITPR3 / IP3R3 antibody WB image
Western blot: 25 µg of LO2 cell lysate stained with ARG58886 anti-ITPR3 / IP3R3 antibody at 1:3000 dilution.
