ARG58823
anti-ITPR3 / IP3R3 antibody
anti-ITPR3 / IP3R3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ITPR3 / IP3R3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Chk |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ITPR3 / IP3R3 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 70-95 of Human ITPR3 (QYWKAKQTKQDKEKIADVVLLQKLQH). |
| 偶联标记 | Un-conjugated |
| 別名 | IP3R; Type 3 inositol 1,4,5-trisphosphate receptor; Inositol 1,4,5-trisphosphate receptor type 3; Type 3 InsP3 receptor; InsP3R3; IP3R 3; IP3 receptor isoform 3; IP3R3 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ITPR3 |
| 全名 | inositol 1,4,5-trisphosphate receptor, type 3 |
| 背景介绍 | This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010] |
| 生物功能 | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 304 kDa |
| 翻译后修饰 | Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues (By similarity). [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG58823 anti-ITPR3 / IP3R3 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse intestine stained with ARG58823 anti-ITPR3 / IP3R3 antibody.
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ARG58823 anti-ITPR3 / IP3R3 antibody WB image
Western blot: 40 µg of HeLa and SW620 cell lysates stained with ARG58823 anti-ITPR3 / IP3R3 antibody at 0.5 µg/ml dilution.
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ARG58823 anti-ITPR3 / IP3R3 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat intestine stained with ARG58823 anti-ITPR3 / IP3R3 antibody.
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ARG58823 anti-ITPR3 / IP3R3 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human lung cancer stained with ARG58823 anti-ITPR3 / IP3R3 antibody.
