ARG66166
anti-IRX3 antibody
anti-IRX3 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IRX3 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IRX3 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around aa. 240 - 320 (Center) of Human IRX3. |
| 偶联标记 | Un-conjugated |
| 別名 | IRX-1; Homeodomain protein IRXB1; Iroquois-class homeodomain protein IRX-3; IRXB1; Iroquois homeobox protein 3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P78415 Human Iroquois-class homeodomain protein IRX-3 Swiss-port # P81067 Mouse Iroquois-class homeodomain protein IRX-3 |
|---|---|
| 基因名称 | IRX3 |
| 全名 | iroquois homeobox 3 |
| 背景介绍 | IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009] |
| 生物功能 | Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity). [UniProt] |
| 细胞定位 | Nucleus |
| 预测分子量 | 52 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66166 anti-IRX3 antibody
Immunohistochemistry: Paraffin-embedded Human breast carcinoma stained with ARG66166 anti-IRX3 antibody (left) at 1:50 dilution, or the same antibody pre-incubated with antigen (right).
