ARG45230
anti-IRS2 antibody
anti-IRS2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IRS2 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IRS2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human IRS2. |
| 偶联标记 | Un-conjugated |
| 別名 | IRS2; Insulin Receptor Substrate 2; |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 180 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IRS2 |
| 全名 | Insulin Receptor Substrate 2 |
| 背景介绍 | This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008] |
| 生物功能 | Signaling adapter protein that participates in the signal transduction from two prominent receptor tyrosine kinases, insulin receptor/INSR and insulin-like growth factor I receptor/IGF1R. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 137 kDa |
| 翻译后修饰 | Isopeptide bond; Methylation; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45230 anti-IRS2 antibody IHC-P image
Immunohistochemistry: Human liver cancer stained with ARG45230 anti-IRS2 antibody at 2 μg/ml dilution.
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ARG45230 anti-IRS2 antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45230 anti-IRS2 antibody at 5 ug/ml dilution.
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ARG45230 anti-IRS2 antibody WB image
Western blot: Hela stained with ARG45230 anti-IRS2 antibody at 0.5 μg/ml dilution.
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ARG45230 anti-IRS2 antibody FACS image
Flow Cytometry: 293T stained with ARG45230 anti-IRS2 antibody at 1 µg/10^6 cells dilution.
