ARG46219
anti-IRGM antibody
anti-IRGM antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IRGM |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IRGM |
| 抗原物种 | Human |
| 抗原 | A 17 amino acid synthetic peptide within aa. 30 - 80 of human IRGM. |
| 偶联标记 | Un-conjugated |
| 別名 | immunity-related GTPase family, M; IRGM; IFI1; IRGM1; LRG47; LRG-47; IFI1; Immunity-related GTPase family M protein; Immunity-related GTPase family M protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 20 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -269°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # A1A4Y4 Human Immunity-related GTPase family M protein Swiss-port # Q6AYC2 Rat Immunity-related GTPase family M protein |
|---|---|
| 基因名称 | IRGM |
| 全名 | immunity-related GTPase family, M |
| 背景介绍 | This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016] |
| 生物功能 | Immunity-related GTPase that plays important roles in innate immunity and inflammatory response. [UniProt] |
| 细胞定位 | Cytoplasm; Cell membrane ; Endosome; Lysosome membrane; Cell projection; Cytoplasmic vesicle; Golgi apparatus. [UniProt] |
| 预测分子量 | 20 kDa |
| 翻译后修饰 | Ubl conjugation. [UniProt] |
